Feline Mycoplasma
Feline Mycoplasma
Mycoplasma species are small bacteria that lack a peptidoglycan cell wall. They belong to the normal commensal flora of the conjunctiva and upper airways (pharynx, larynx, oral cavity, nasal cavity) in cats and are a well-recognized cause of conjunctivitis and upper respiratory infection in this species. This disease can cause death if not diagnosed and treated by a veterinarian. Over 100 species have been included in the genus Mycoplasma. Microbes of the class Mollicutes, to which Mycoplasma belongs, are parasites or commensals of humans, animals, and plants. The genus Mycoplasma uses vertebrate and arthropod hosts. Dietary nitrogen availability has been shown to alter codon bias and genome evolution in Mycoplasma and Phytoplasma.
Symptoms
Anemia.
Lethargy.
Lack of appetite.
Weakness.
Fever.
Yellowing of skin (Jaundice)
Pale skin and mucous membranes.
Nasal or ocular (eye) discharge.
Weak newborns, stillbirths, early death of newborns, or death while in embryo.
Diagnosis
PCR Upper Respiratory Panel
https://www.idexx.com/en/veterinary/reference-laboratories/idexx-realpcr-tests/
https://tvmdl.tamu.edu/tests/feline-upper-respiratory-panel-qpcr/
Bacterial Culture (Sensitivity test suggested)
Treatment
Only Gram-Negative Antibiotics Are Effective
Doxycycline (Preferred treatment)
(34mg) per 5lbs of cat
Enrofloxacin
(5 mg/kg/day, PO) is a suitable alternative to doxycycline.
Enrofloxacin given at 5 mg/kg, PO, every 24 hours or at 10 mg/kg, PO, every 24 hours for 14 days is tolerated by cats and is
Equally effective or more effective than doxycycline
Azithromiacin
Albuterol sulfate (Repository Distress)
Prevention
Mycoplasma genitalium (mycoplasma) has recently been identified as a sexual transmitted infection and is a bacteria that infects the mucous membranes of the urethra,cervix, throat and anus. Mycoplasma is transmitted by vaginal, anal and oral sex.
Resources
https://www.merckvetmanual.com/circulatory-system/blood-parasites/hemotropic-mycoplasmas#v3257810
http://citeseerx.ist.psu.edu/viewdoc/download?doi=10.1.1.1009.7562&rep=rep1&type=pdf
https://veterinary-practice.com/article/treatment-of-mycoplasma-spp-infections-in-cats